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. 2024 Mar 11;15:1356075. doi: 10.3389/fimmu.2024.1356075

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Copyright © 2024 Lv, Mu, Zhang, Zhao, Jiang, Xiao, Sun, Wu, Sun and Jin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single-cell transcriptional analysis reveals the cell communication in CRC and IBD. (A) Analysis of the number of interactions and interaction strength between different cell types in CRC samples. (B) Analysis of the number of interactions and interaction strength between different cell types in IBD samples. (C) Identification of signaling by comparing the communication probabilities mediated by ligand-receptor pairs from macrophages to other cell types in CRC and IBD samples. (D, E) Overview of the outgoing signaling and incoming signaling in CRC and IBD samples.