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. 2024 Mar 11;15:1356075. doi: 10.3389/fimmu.2024.1356075

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Copyright © 2024 Lv, Mu, Zhang, Zhao, Jiang, Xiao, Sun, Wu, Sun and Jin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MPs and their functional annotations in CRC and IBD. (A) Heatmap showing Jaccard similarity indices for comparisons among 71 robust NMF programs of epithelial cells. The programs are ordered by clustering and grouped into four MPs with their related functions (marked by black dashed lines). The disease types are numbered and labeled. (B) Heatmap showing Jaccard similarity indices for comparisons among 151 robust NMF programs of immune cells. A total of seven MPs with their related functions were recognized in CRC immune cells, and two MPs were recognized in IBD immune cells (marked by black dashed lines).