Table 1.
Characteristics of 53 patients with locally advanced rectal cancer.
| pCR (n=15), n (%) | Non-pCR (n=38), n (%) | P value | |
|---|---|---|---|
| Sex | 0.333 | ||
| Female | 6 (40) | 10 (26.3) | |
| Male | 9 (60) | 28 (73.7) | |
| Age (y) | 0.114 | ||
| Mean ± SD | 52.7 ± 13.6 | 58.6 ± 11.4 | |
| CEA level | 0.230 | ||
| Normal | 11 (73.3) | 21 (55.3) | |
| Abnormal | 4 (26.7) | 17 (44.7) | |
| Gross tumor volume (cm3) | 0.040⁎ | ||
| Mean ± SD | 27.0 ± 14.0 | 46.8 ± 40.7 | |
| Tumor location (from anal verge) | 0.765 | ||
| Low | 8 (53.3) | 22 (57.9) | |
| Middle | 7 (46.7) | 16 (42.1) | |
| High | 0 | 0 | |
| Tumor differentiation | 0.000⁎ | ||
| Poor | 1 (6.7) | 11 (28.9) | |
| Moderate | 5 (33.3) | 24 (63.2) | |
| Well | 9 (60) | 3 (7.9) | |
| cTNM stage at baseline | 0.111 | ||
| I-II | 1 (6.7) | 0 | |
| III | 14 (93.3) | 38 (100) | |
| mrT stage at baseline | 0.072 | ||
| T1-2 | 2 (13.3) | 2 (5.3) | |
| T3 | 11 (73.4) | 22 (57.9) | |
| T4 | 2 (13.3) | 14 (36.8) | |
| mrN stage at baseline | 0.483 | ||
| N0-1 | 2 (13.3) | 9 (23.7) | |
| N2 | 13 (86.7) | 29 (76.3) | |
| mrTD status at baseline | 0.243 | ||
| Negative | 11 (73.4) | 33 (86.8) | |
| Positive | 4 (26.7) | 5 (13.2) | |
| mrEMVI status at baseline | 0.314 | ||
| Negative | 2 (13.3) | 10 (26.3) | |
| Positive | 13 (86.7) | 28 (73.7) | |
| mrCRM status at baseline | 0.509 | ||
| Negative | 4 (26.7) | 7 (18.4) | |
| Positive | 11 (73.3) | 31 (81.6) |
pCR, pathologic complete response; SD, standard deviation; TD, tumor deposit; EVMI, extramural vascular invasion; CRM, circumferential resection margin; CEA, carcinoembryonic antigen.
*Signifies a significant difference between pCR and non-pCR groups (P < 0.05).