Table 1.

L-TRRiP model

Factor	Coefficient
Male sex	0.63
Type of first VTE
PE	−0.61
PE+DVT	0.32
Location of DVT
Popliteal DVT*	−0.46
Surgery†	−0.51
Pregnancy/puerperium†	−1.49
Hormone use‡	−0.67
Plaster cast†	−0.79
Immobility in bed, in hospital†§	−0.31
History of cardiovascular disease¶	−0.35
Blood group, non-O	0.24
Factor V Leiden mutation**	0.40
Calculation of the L-TRRiP score
Prognostic score	Beta1*x1+beta2*x2+beta3*x3 + …. The x1, x2, x3, etc, represent the factors in the model, and beta1, beta2, beta3, etc, represent the corresponding coefficients.
Absolute 2-year risk of VTE recurrence	0.9235595ˆexp(prognostic score)
Classification of patients with the L-TRRiP score
Low recurrent VTE risk	2-year risk <0.06
Intermediate recurrent VTE risk	2-year risk 0.06–0.14
High recurrent VTE risk	2-year risk >0.14

Table adapted from Timp et al. ¹⁷

*DVT at the level of the vena poplitea or below.

†Within 3 months before VTE.

‡Use of hormonal contraceptives or hormone replacement therapy at the time of VTE.

§Confinement to bed ≥3 days.

¶Including a history of heart failure, angina pectoris, peripheral artery vascular disease (claudication), acute myocardial infarction.

**Homozygous or heterozygous.

DVT, deep venous thrombosis; L-TRRiP, Leiden Thrombosis Recurrence Risk Prevention; PE, pulmonary embolism; VTE, venous thromboembolism.