Table 1. Percentage of DOTA Bonded to Each mAb Domain.

domain	measured fragment	% DOTA
VH		11a
CH1	[137–213]	0
CH2		12.5b
CH3	[344–442]	13
VL	[1–108]	0
CL		6c

^aValue calculated using the formula (VH + DOTA) = [(Fab_HC + DOTA) – (CH1 + DOTA)].

^bValue calculated using the formula (CH2 + DOTA) = {(HC + DOTA) – [(Fab_HC + DOTA) + (CH3 + DOTA)]}.

^cValue calculated using the formula (CL + DOTA) = [(LC + DOTA) – (VL + DOTA)].