Table 3.

Cox proportional hazard Model of HGI (as continuous variable).

	All cause death (per 1% increase)			CV death (per 1% increase)			MACE (per 1% increase)
	HR	95% CI	P value	HR	95% CI	P value	HR	95% CI	P value
Unadjusted Model	0.889	[0.798 0.991]	0.033	0.819	[0.696 0.964]	0.016	1.074	[0.989 1.150]	0.085
Adjusted with Model 1	0.845	[0.757 0.944]	0.003	0.774	[0.659 0.909]	0.001	1.042	[0.972 1.117]	0.249
Adjusted with Model 2	0.859	[0.772 0.956]	0.005	0.781	[0.666 0.914]	0.002	1.029	[0.959 1.103]	0.425
Adjusted with Model 3	0.875	[0.787 0.973]	0.014	0.792	[0.676 0.928]	0.004	1.031	[0.961 1.104]	0.399

Model 1: Age + Sex + Hypertension + Diabetes + Atrial fibrillation + Prior stroke + Prior myocardial infarction + BMI; Model 2: Model 1 + Systolic blood pressure + Diastolic blood pressure + Heart rate + LVEF + BNP + Haemoglobin + CRP + HDL-C; Model 3: Model 2 + Beta-blockers + ACEIs/ARBs + Spirolactone. ACEIs/ARBs: Angiotensin-converting enzyme inhibitors/Angiotensin receptor inhibitors; BMI: body mass index; BNP: B-type natriuretic peptide; CI: confidence interval; CRP: C-creative protein; CV death: cardiovascular death; HDL-C: high density lipoprotein-cholesterol; HGI: haemoglobin glycation index; HR: hazard ratio; LVEF: left ventricular ejection fraction; MACE: major adverse cardiac events.