TABLE 1.
Subtype-specific variation in the HIV-1 DIS
| HIV-1 subtype or group | No. of isolates examined
|
No. with indicated DIS
|
|||
|---|---|---|---|---|---|
| By sequencing | By restriction analysisb | GTGCAC, DIS (TA) | GCGCGC, DIS (CG) | GTGCGC, DIS (TG) | |
| Subtype | |||||
| A | 2 | 18 | 20 | 0 | 0 |
| B | 17 | 5 | 0 | 22 | 0 |
| C | 2 | 5 | 7 | 0 | 0 |
| D | 3 | 5 | 0 | 7 | 1 |
| E | 3 | 0 | 3 | 0 | 0 |
| F | 0 | 5 | 5 | 0 | 0 |
| G | 3 | 1 | 3 | 0 | 1 |
| Othera | 4 | 0 | 4 | 0 | 0 |
| Group O | 2 | 0 | 2 | 0 | 0 |
a
A/D and A/C intersubtype recombinants.
b
Restriction endonucleases ApaLI, BssHII, and FspI were used to distinguish DIS sequences as described in Materials and Methods.