Table 2.
Lesion-based quantitative PET/MRI characteristics at baseline and early response evaluation, and additional delta parameters
| Description | Median (IQR) | Minimum | Maximum |
|---|---|---|---|
| Baseline | |||
| SUVmax | 11.33 (10.09 to 12–49) | 6.72 | 27.31 |
| SUVmean | 7.39 (6.56–8.31) | 4.56 | 18.76 |
| FTV | 14.36 (8.15–38.60) | 1.98 | 171.11 |
| T2_LL | 61.01 (51.56–67.03) | 31.36 | 82.50 |
| T2_AP | 39.10 (38.24–56.29) | 29.12 | 76.48 |
| T2 CC | 30 (28.5–40.5) | 27 | 87 |
| ADC LL | 45.70 (40.42–55.54) | 13.35 | 94.21 |
| ADC AP | 40.07 (31.99–57.30) | 10.54 | 77.34 |
| ADC CC | 30 (25–42.5) | 10 | 75 |
| ADC | 1021 (929.5–1053) | 848 | 1312 |
| Early response evaluation | |||
| SUVmax | 10.32 (9.84–13.17) | 8.97 | 21.63 |
| SUVmean | 6.97 (6.16–8.41) | 5.71 | 14.27 |
| FTV | 8.49 (5.6–26.9) | 2.39 | 232.91 |
| T2_LL | 51.56 (44.25–62.52) | 28.79 | 79.49 |
| T2_AP | 38.67 (32.44–47.91) | 19.77 | 72.62 |
| T2 CC | 39 (31.5–39) | 15 | 78 |
| ADC LL | 40.07 (34.45–62.34) | 18.98 | 83.67 |
| ADC AP | 35.85 (29.88–49.21) | 22.50 | 73.83 |
| ADC CC | 30 (22–40) | 15 | 65.02 |
| ADC | 1062 (1001–1221) | 975 | 1333 |
| Delta | |||
| SUVmax | 0.91 (− 1.52 to 2.32) | − 10.59 | 13.12 |
| SUVmean | 0.95 (− 0.90 to 1.26) | − 6.88 | 9.37 |
| FTV | 1.54 (0.33–3.9) | − 61.79 | 21.99 |
| T2_LL | 3.86 (2.79–7.94) | − 2.15 | 16.22 |
| T2_AP | 3.86 (− 0.21 to 7.94) | − 5.59 | 22.34 |
| T2 CC | (− 6.00 to 7.5) | − 12 | 12 |
| ADC LL | 2.10 (− 5.97 to 7.38) | − 15.71 | 20.39 |
| ADC AP | 0.00 (− 5.62 to 6.67) | − 11.95 | 20.39 |
| ADC CC | 5.00 (0.00–10) | − 15 | 25 |
| ADC | 70 (41–141) | − 27 | 242 |
SUV max = maximum standardized uptake value, SUV mean = mean standardized uptake value, FTV = functional tumor volume, T2 LL = maximum lateral-lateral tumor diameter measured on T2W, T2 AP = maximum anteroposterior tumor diameter measured on T2W, T2 CC = craniocaudal tumor diameter measured on T2W, ADC LL = laterolateral tumor diameter measured on apparent diffusion coefficient map, ADC AP = anteroposterior tumor diameter measured on apparent diffusion coefficient map, ADC CC = craniocaudal tumor diameter measured on apparent diffusion coefficient map, ADC = tumor apparent diffusion coefficient value