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. 2023 Jun 2;24(13):e202200756. doi: 10.1002/cbic.202200756

Scheme 2.

Scheme 2

Synthesis of compounds 13 a, 15 a, 17 a20 a, 22 a and 24 a suitable for reaction with oligonucleotides using click chemistry. The compounds contain an alkyne handle, a flexible linker and a metal‐binding group.