TABLE 3.
Cross-reactivity of T-cell lines generated from PBMC of patient KPP94-037 1 year after dengue virus infectiona
| Line | Phenotype | % Specific 51Cr releaseb
|
|||
|---|---|---|---|---|---|
| Vac.control | Vac.D1ENS1.2a | Vac.D2NS1.2a | Vac.D4NS1.2a | ||
| 2G3 | CD4+ | 0 | 57 | 91 | 64 |
| 2E8 | CD4+ | 5 | 59 | 81 | 67 |
| 2D11 | CD4+ | 5 | 64 | 98 | 73 |
| 2B5 | CD4+ | 9 | 59 | 93 | 73 |
| 3C11 | CD8+ | 9 | 56 | 80 | 59 |
| 3E7 | CD8+ | 8 | 57 | 97 | 100 |
| 3F3 | CD8+ | 8 | 65 | 100 | 57 |
| 2C8 | CD8+ | 9 | 63 | 89 | 78 |
| 2G7 | CD8+ | 4 | 56 | 77 | 58 |
| 2D9 | CD8+ | 5 | 58 | 96 | 65 |
| 3F11 | CD8+ | 3 | 51 | 67 | 40 |
| 3G10 | CD8+ | 4 | 66 | 80 | 59 |
T-cell lines were established from bulk culture of PBMC from patient KPP94-037 by the limiting-dilution method. The phenotype of the cells was determined by fluorescent antibody staining.
Measured at E/T ratios between 20:1 and 60:1 for all T-cell lines used.