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[Preprint]. 2024 Feb 24:2024.02.21.581451. [Version 2] doi: 10.1101/2024.02.21.581451

Table 4. Quantification of in vivo pharmacokinetics of BrMeI versus bromocriptine in mice.

Data are represented as the mean ± SEM (n=3 per group).

Drug Time (min) Plasma Conc. (nmol/L) Brain Conc. (pmol/g) Brain/Plasma Ratio
Bromocriptine 15 min 1336.7 ± 52.2 995.2 ± 188.0 0.74 ± 0.11
60 min 158.6 ± 15.0 71.1 ± 2.3 0.45 ± 0.05
BrMel 15 min 4259.1 ± 381.3 1282.3 ± 130.7 0.30 ± 0.03
60 min 1277.1 ± 71.1 651.9 ± 133.7 0.51 ± 0.06