TABLE 3.
Sequence composition of libraries of integration sites and control DNA fragments
| Sequence class | Analysis of 144-bp sequences (avg length)a
|
Reanalysis of 50-bp sequencesb
|
||
|---|---|---|---|---|
| Integration sites (%) | Genomic DNA (%) | Integration sites (%) | Genomic DNA (%) | |
| Anonymous | 61 | 43 | 69 | 71 |
| Alu element | 10 | 9 | 10 | 6 |
| LINE element | 8 | 13 | 2 | 6 |
| Alphoid repeat | 0 | 6 | 0 | 3 |
| Other repeats | 7 | 22 | 3 | 10 |
| Transcription unit | 18 | 8 | 16 | 4 |
a
For data from sequences of 144-bp average length, 61 integration sites and 104 control sequences were considered.
b
For the reanalysis of integration site sequences considering only the proximal 50 bp of human DNA sequence, 58 integration sites and 104 control sequences were considered.