Table 1.

Genome-wide significant loci for EduYears in EAS population

Chr	Start	End	Credible set ID	Credible set size	Total PIP	N of significant variantsa	SNP with maximum PIP	Maximum PIP	A1	Effect size	A1 Freq	Marginal P value	Gene	Annotation
2	161,721,597	162,351,261	1	6	0.96	6	rs10930013	0.26	A	−0.021	0.42	7.80 × 10−10	TANK	Intron
4	180,613,679	181,136,169	1	4	0.95	4	rs2871133	0.36	C	−0.020	0.53	3.54 × 10−9	NA	NA
5	93,838,858	94,392,030	1	20	0.95	19	rs255347	0.11	T	0.022	0.73	5.70 × 10−9	MCTP1	Intron
5	106,947,725	107,455,182	1	2	0.96	2	rs7708343	0.62	A	−0.021	0.32	4.46 × 10−9	FBXL17	Intron
6	27,515,505	29,611,229	1	13	0.95	3	rs9461540	0.47	G	−0.027	0.17	6.19 × 10−10	GABBR1	Upstream gene
6	27,515,505	29,611,229	2	6	0.96	6	rs16893804	0.40	G	−0.028	0.22	5.62 × 10−12	NA	NA
10	103,385,878	104,057,295	1	27	0.96	18	rs11191157	0.60	A	−0.023	0.22	2.34 × 10−8	C10orf76	Intron
17	42,899,988	43,438,117	1	10	0.95	10	rs12936234	0.20	C	0.020	0.47	4.28 × 10−9	NMT1	Intron

Abbreviations: A1 Freq, frequency of A1; A1, effect allele; Chr, chromosome; N, number; NA, not available. Gene symbols are italicized.

^aNumber of genome-wide significant variants with P value of a two-sided test <5 × 10⁻⁸.

Base pair position is based on the human genome assembly GRCh37 (hg19).

‘Credible set ID’: the ID of credible sets used to identify different credible sets in the same region.

‘Gene’: the genes affected by the variant using the Variant Effect Predictor tool.

‘Annotation’: the consequence of variants on the protein sequence using the Variant Effect Predictor tool.