Table 3.
Between-group effect sizes of depressive and anxiety symptoms for transdiagnostic treatments compared to control groups at follow-up
| Depression | Anxiety | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| k | g | P | LL | UL | I2 | Q | P | k | g | P | LL | UL | I2 | Q | P | |||
| 3 month FU | TD-CBT (all treatment formats) versus | Control | 29 | 0.55 | <0.001 | 0.30 | 0.80 | 89.98 | 143.19 | <0.001 | 24 | 0.48 | 0.002 | 0.18 | 0.79 | 92.31 | 131.28 | <0.001 |
| DS-CBT | 5 | 0.11 | 0.376 | −0.14 | 0.37 | 77.81 | 15.73 | 0.003 | 5 | −0.01 | 0.912 | −0.18 | 0.16 | 52.62 | 8.48 | 0.075 | ||
| TAU | 6 | 0.42 | <0.001 | 0.26 | 0.59 | 6.45 | 6.77 | 0.238 | 4 | 0.49 | <0.001 | 0.22 | 0.76 | 51.43 | 6.24 | 0.101 | ||
| Other | 10 | 0.33 | 0.014 | 0.07 | 0.59 | 57.15 | 20.99 | 0.013 | 8 | 0.24 | 0.009 | 0.06 | 0.42 | 0 | 9.69 | 0.207 | ||
| WL | 8 | 1.29 | 0.002 | 0.47 | 2.10 | 93.43 | 70.96 | <0.001 | 7 | 1.31 | 0.016 | 0.24 | 2.37 | 94.84 | 77.31 | <0.001 | ||
| Individual TD-CBT versus | Control | 8 | 1.38 | <0.001 | 0.64 | 2.13 | 90.69 | 51.37 | <0.001 | 5 | 1.88 | 0.002 | 0.72 | 3.03 | 91.25 | 50.83 | <0.001 | |
| Group-based TD-CBT versus | Control | 12 | 0.39 | 0.002 | 0.14 | 0.63 | 74.49 | 31.78 | <0.001 | 10 | 0.42 | <0.001 | 0.20 | 0.65 | 61.80 | 22.45 | 0.008 | |
| Internet-based TD-CBT versus | Control | 9 | 0.18 | 0.127 | −0.05 | 0.42 | 73.17 | 27.64 | <0.001 | 9 | −0.05 | 0.409 | −0.17 | 0.07 | 2.55 | 7.89 | 0.444 | |
| 6 month FU | TD-CBT (all treatment formats) versus | Control | 17 | 0.20 | <0.001 | 0.10 | 0.30 | 17.75 | 24.09 | 0.088 | 19 | 0.23 | <0.001 | 0.11 | 0.36 | 42.99 | 34.74 | 0.010 |
| DS-CBT | 3 | −0.01 | 0.937 | −0.23 | 0.21 | 39.89 | 3.28 | 0.194 | 3 | 0.04 | 0.650 | −0.15 | 0.24 | 22.99 | 2.33 | 0.312 | ||
| TAU | 4 | 0.26 | <0.001 | 0.15 | 0.38 | 0 | 0.74 | 0.864 | 4 | 0.32 | 0.001 | 0.13 | 0.52 | 47.22 | 5.67 | 0.129 | ||
| Other | 7 | 0.15 | 0.163 | −0.06 | 0.37 | 10.92 | 6.13 | 0.409 | 8 | 0.19 | 0.050 | 0 | 0.38 | 0 | 6.19 | 0.518 | ||
| WL | 3 | 0.63 | 0.019 | 0.10 | 1.15 | 47.71 | 3.82 | 0.148 | 4 | 0.62 | 0.065 | −0.04 | 1.27 | 77.44 | 11.90 | 0.008 | ||
| Individual TD-CBT versus | Control | 9 | 0.24 | 0.012 | 0.05 | 0.44 | 44.45 | 14.07 | 0.080 | 10 | 0.28 | <0.001 | 0.18 | 0.38 | 0 | 18.92 | 0.026 | |
| Group-based TD-CBT versus | Control | 8 | 0.16 | 0.033 | 0.01 | 0.31 | 16.49 | 9.45 | 0.222 | 9 | 0.17 | 0.065 | −0.01 | 0.36 | 46.53 | 14.41 | 0.072 | |
| Internet-based TD-CBT versus | Control | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
| 12 month FU | TD-CBT (all treatment formats) versus | Control | 11 | 0.24 | <0.001 | 0.13 | 0.35 | 33.53 | 13.48 | 0.198 | 11 | 0.22 | <0.001 | 0.12 | 0.32 | 24.83 | 10.52 | 0.396 |
| DS-CBT | 4 | 0.13 | 0.247 | −0.09 | 0.36 | 58.91 | 7.48 | 0.058 | 4 | 0.08 | 0.253 | −0.06 | 0.23 | 0 | 0.87 | 0.832 | ||
| TAU | 4 | 0.35 | <0.001 | 0.24 | 0.47 | 0 | 0.30 | 0.960 | 4 | 0.36 | <0.001 | 0.24 | 0.48 | 0 | 0.70 | 0.872 | ||
| Other | 3 | 0.23 | 0.030 | 0.02 | 0.44 | 0 | 0.03 | 0.985 | 3 | 0.21 | 0.044 | 0.01 | 0.42 | 0 | 0.10 | 0.950 | ||
| WL | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | ||
| Individual TD-CBT versus | Control | 3 | 0.33 | <0.001 | 0.21 | 0.45 | 0 | 0.58 | 0.748 | 3 | 0.34 | <0.001 | 0.20 | 0.47 | 9.71 | 1.67 | 0.434 | |
| Group-based TD-CBT versus | Control | 3 | 0.30 | 0.006 | 0.09 | 0.51 | 0 | 0.59 | 0.745 | 3 | 0.27 | 0.012 | 0.06 | 0.48 | 0 | 0.24 | 0.888 | |
| Internet-based TD-CBT versus | Control | 5 | 0.17 | 0.098 | −0.03 | 0.38 | 54.63 | 8.93 | 0.063 | 5 | 0.11 | 0.116 | −0.03 | 0.24 | 0 | 1.95 | 0.746 | |
| 24 month FU | TD-CBT (all treatment formats) versus | Control | 5 | 0.20 | 0.111 | −0.05 | 0.46 | 80.63 | 16.44 | 0.003 | 5 | 0.14 | 0.092 | −0.02 | 0.31 | 56.46 | 8.63 | 0.071 |
| DS-CBT | 4 | 0.20 | 0.259 | −0.14 | 0.54 | 81.90 | 16.15 | 0.001 | 4 | 0.11 | 0.344 | −0.12 | 0.35 | 62.33 | 8.25 | 0.041 | ||
| TAU | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | ||
| Other | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | ||
| WL | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | ||
| Individual TD-CBT versus | Control | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
| Group-based TD-CBT versus | Control | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
| Internet-based TD-CBT versus | Control | 4 | 0.20 | 0.259 | −0.14 | 0.54 | 81.90 | 16.15 | 0.001 | 4 | 0.11 | 0.344 | −0.12 | 0.35 | 62.33 | 8.25 | 0.041 | |
FU, follow-up.