Table 4.
NEFL results.
| Controls | CMTX1 | CMT1B | CMT2A | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NEFL (ng/L) | n | Mean ± SD (Range) | p | n | Mean ± SD (Range) | p | n | Mean ± SD (Range) | p | n | Mean ± SD (Range) | p |
| Baseline | 14 | 6.6 ± 3.2 (3.5–15.9) | NA | 21 | 13.6 ± 4.6 (5.9–20.5) | 0.007 | 21 | 18.8 ± 8.8 (4.8–38.0) | <0.001 | 20 | 17.3 ± 5.4 (9.3–29.3) | <0.001 |
| Annual change | 14 | 0.3 ± 1.2 (−1.2–3.3) | 0.34 | 17 | −1.4 ± 2.4 (−6.7–2.0) | 0.09 | 20 | −1.4 ± 3.4 (−8.7–6.0) | 0.07 | 18 | −0.3 ± 2.8 (−6.9–4.0) | 0.90 |
| Correlation of NEFL | n | R | p | n | R | p | n | R | p | n | R | p |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| With age | 14 | 0.76 | 0.002 | 21 | −0.24 | 0.30 | 21 | 0.54 | 0.01 | 20 | 0.15 | 0.53 |
| With calf muscle FF | 14 | 0.63 | 0.02 | 21 | −0.62 | 0.003 | 19 | 0.25 | 0.30 | 19 | 0.15 | 0.54 |
Baseline and annualised change values, and Spearman rank correlation with age and fat fraction are given in patient and control groups. p‐Value for baseline patient values are compared with control (Tukey HSD), while for change values are paired Student t‐tests.