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. 2024 Mar 14;10(6):e28078. doi: 10.1016/j.heliyon.2024.e28078

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© 2024 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 1 — Schematic representation of monoterpene indole alkaloids (MIA) biosynthetic pathway. MEP: methylerythritol phosphate, DAHP: 3-deoxy-D-arabino-heptulosonate-7-phosphate, TDC: tryptophan decarboxylase, IDI: isopentenyl-diphosphate Delta-isomerase, DXS: 1-deoxy-D-xylulose 5-phosphate synthase, GPPS: geranyl-pyrophosphate synthase, SLS: secologanin synthase, LAMT: loganic acid O-methyltransferase, 7DLH: 7-deoxyloganic acid hydroxylase, 7DLGT: 7-deoxyloganetic acid glucosyl transferase, 7DLS: 7-deoxyloganetic acid synthase, IO: iridoid oxidase, IRS: iridoid synthase, 8HGO: 8-hydroxygeraniol oxidoreductase, G8H: geraniol 8-hydroxylase, STR: strictosidine synthase, SGD: strictosidine β-D-glucosidase, GS: geissoschizine synthase, GO: geissoschizine oxidase, SAT: stemmadenine O-acetyltransferase, PAS: precondylocarpine acetate synthase, DPAS: dihydroprecondylocarpine acetate synthase.