TABLE 3.
HIV-2 infection of wild-type and Δ32/Δ32 PBMCsa
| Virus | RT activity (pg/ml) in supernatants after culture in PBMCs
|
|||||
|---|---|---|---|---|---|---|
| Day 2
|
Day 5
|
Day 9
|
||||
| Δ32 | wt | Δ32 | wt | Δ32 | wt | |
| MIR | 117 | 292 | 446 | 415 | >500 | >500 |
| A-ND | 264 | 283 | 441 | 328 | >500 | >500 |
| ST | 86 | 193 | 577 | 407 | >500 | >500 |
| prCBL-20 | 72 | 121 | 309 | 477 | >500 | >500 |
| CBL-20 | 112 | 108 | 484 | >500 | >500 | >500 |
| prCBL-23 | 11 | <4 | 158 | 61 | >500 | >500 |
a
Virus isolates were tested for their ability to infect PBMCs from an individual who is homozygous for the Δ32 deletion in the CCR5 gene and from an individual homozygous for wild-type (wt) CCR5 gene. PBMCs were infected, and supernatants were analyzed for RT activity on days 2, 5, and 9.