Table 2. Histogram metrics between IDH-M and IDH-W gliomas and ROC results.
| Quantitative maps | Parameters | IDH-M (N=41) | IDH-W (N=39) | t/Z value | P value | AUC (95% CI) | Cut-off value | Sen. (%) | Spe. (%) |
|---|---|---|---|---|---|---|---|---|---|
| T1map (×103 ms) | T1-10th | 1.06±0.14 | 1.20±0.20 | 3.375 | <0.001* | 0.735 (0.624–0.827) | ≤1.09 | 63.41 | 79.49 |
| T1-mean | 1.45 (1.32, 1.60) | 1.58 (1.41, 1.71) | −2.026 | 0.043# | 0.632 (0.516–0.737) | ≤1.52 | 63.41 | 64.10 | |
| T1-median | 1.38 (1.30, 1.55) | 1.52 (1.39, 1.60) | −1.978 | 0.048# | 0.629 (0.513–0.734) | ≤1.40 | 53.66 | 76.92 | |
| T1map+C (×103 ms) | cT1-10th | 0.87 (0.73, 1.04) | 0.54 (0.48, 0.64) | −4.845 | <0.001# | 0.819 (0.717–0.896) | >0.68 | 78.05 | 84.62 |
| cT1-mean | 1.31 (1.11, 1.47) | 0.98 (0.85, 1.20) | −3.056 | 0.002# | 0.699 (0.586–0.796) | >1.16 | 73.17 | 71.79 | |
| cT1-median | 1.28 (1.07, 1.46) | 0.81 (0.76, 1.16) | −3.547 | <0.001# | 0.730 (0.620–0.824) | >1.06 | 75.61 | 71.79 | |
| cT1-minimum | 0.43 (0.31, 0.61) | 0.29 (0.17, 0.37) | −3.364 | 0.001# | 0.719 (0.607–0.813) | >0.38 | 58.54 | 84.62 | |
| PDmap+C (pu) | cPD-10th | 75.29±5.91 | 79.28±5.35 | 3.157 | 0.002* | 0.704 (0.591–0.801) | ≤76.90 | 68.29 | 66.67 |
| cPD-90th | 93.60 (89.25, 99.90) |
101.20 (95.18, 103.58) |
−3.085 | 0.002# | 0.700 (0.588–0.798) | ≤97.50 | 73.17 | 71.79 | |
| cPD-mean | 84.79±5.45 | 90.56±5.04 | 4.914 | <0.001* | 0.792 (0.687–0.875) | ≤87.28 | 78.05 | 76.92 | |
| cPD-median | 84.90 (83.05±88.65) | 89.93 (87.10±94.40) | −3.090 | 0.002# | 0.701 (0.588–0.798) | ≤86.90 | 68.29 | 76.92 | |
| cPD-maximum | 109.20 (106.40, 117.95) |
118.60 (112.25, 124.33) |
−3.124 | 0.002# | 0.703 (0.590–0.800) | ≤109.30 | 58.54 | 82.05 |
Continuous quantitative variables as mean ± standard deviation or median (first quartile and third quartile). *, P value represents the comparison results of IDH-M and IDH-W gliomas using the t-test analysis; #, P value represents the comparison results of IDH-M and IDH-W gliomas using the non-parametric Mann-Whitney U-test. IDH-M, isocitrate dehydrogenase mutant; IDH-W, isocitrate dehydrogenase wildtype; ROC, receiver operating characteristic; T1map+C, post-contrast T1map; PDmap+C, post-contrast PDmap; AUC, area under the curve; CI, confidence interval; Sen., sensitivity; Spe., specificity; 10th, 10th percentile; 90th, 90th percentile; cT1, post-contrast T1; cPD, post-contrast PD.