Table 2.
Histological analysis of Liver, Stomach and Kidney of animals submitted to periodontitis and treated with Chenopodium ambrosioides extract
| Histopathological Aspects | Experimental Groups | ||||
|---|---|---|---|---|---|
| Naive | SAL | CAL 3 | CAL 10 | CAL 30 | |
| Liver | |||||
| ● Portal and center lobular Vein congestion | 0 (0-2) | 1 (1-2)# | 1 (0-1) | 0 (0-2)* | 1 (0-2) |
| ● Edema of hepatocytes | 0 (0-1) | 1 (0-1)# | 0 (0-1) | 1 (0-1) | 1 (1-2) |
| ● Sinusoidal bleeding | 1 (0-2) | 2 (1-3)# | 1 (0-2) | 1 (1-1)* | 1 (1-2) |
| ● Inflammatory infiltrate | 0 (0-0) | 1 (0-1) | 1 (1-2) | 1 (0-1) | 0 (0-1) |
| Kidneys | |||||
| ● Edema of cells from tubular epithelium | 0 (0-1) | 1 (1-2) | 1 (1-2) | 1 (1-2) | 1 (1-2) |
| ● Vacuolization of cells from tubular epithelium | 0 (0-1) | 1 (1-2) | 1 (1-2)# | 1 (1-2) | 1 (1-2) |
| ● Recent interstitial and tubular bleeding | 1 (0-2) | 2 (1-2) | 1 (1-2) | 1 (1-2) | 1 (1-2) |
| ● Nephrotoxic necrosis | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) |
| ● Loss of cells | 0 (0-1) | 0 (0-2) | 0 (0-2) | 1 (0-2) | 1 (0-1) |
| Stomach-Cardia | |||||
| ● Ectatic vessels | 0 (0-1) | 1 (0-1) | 0 (0-1) | 1 (1-1) | 1 (0-1) |
| ● Bleeding | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) |
| ● Presence of gastric mucosal glands in | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) |
| Stomach–back | |||||
| ● Ectatic vessels | 1 (0-1) | 1 (0-1) | 1 (0-1) | 1 (0-1) | 1 (1-1) |
| ● Bleeding | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) |
| ● Inflammatory Infiltrate | 0 (0-1) | 1 (0-1) | 1 (0-2) | 1 (0-1) | 1 (0-1) |
| ● Loss of cells | 0 (0-1) | 0 (0-2) | 0 (0-1) | 0 (0-1) | 0 (0-2) |
| ● Edema | 0 (0-0) | 1 (0-1) | 1 (1-2)# | 1 (1-2)# | 1 (0-1) |
Sal: Saline group
CAL: Chenopodium ambrosioides
#
: Indicates difference compared to N group
*
: Indicates difference compared to DP group
Kruskal-Wallis and Dunn test (p< 0.05).