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. 2024 Feb 28;21(2):200–210. doi: 10.26599/1671-5411.2024.02.005

Table 2. Independent risk factors for AF after catheter ablation.

Variable Univariate Cox regression analysis Multivariate Cox regression analysis
HR 95% CI P-value HR 95% CI P-value
*Refers to variables included in multivariate Cox regression analysis. AF: atrial fibrillation; T1: the low cumulative triglyceride-glucose index group; T2: the medium cumulative triglyceride-glucose index group; T3: the high cumulative triglyceride-glucose index group.
Female sex 1.226 0.753–1.998 0.413
Age, yrs
 < 65* Reference Reference Reference Reference Referrence Reference
 65–74 0.952 0.530–1.707 0.868 0.974 0.505–1.877 0.937
 ≥ 75 2.169 1.220–3.854 0.008 1.546 0.603–3.966 0.365
Body mass index > 24 kg/m2* 0.680 0.421–1.098 0.114 0.566 0.339–1.052 0.077
Hypertension 1.476 0.900–2.422 0.123
Hyperlipemia* 1.676 0.956–2.939 0.072 1.495 0.822–2.722 0.188
Diabetes mellitus 1.083 0.580–2.022 0.803
Coronary heart disease 1.329 0.806–2.189 0.265
Persistent AF* 1.681 1.041–2.715 0.034 0.872 0.489–1.553 0.642
Duration of AF > 5 yrs* 0.683 0.401–1.163 0.160 0.803 0.462–1.396 0.437
Educational level
 Below primary school* Reference Reference Reference Reference Reference Reference
 Middle school 0.966 0.519–1.800 0.914
 Above college 0.668 0.305–1.465 0.314
Serum uric acid, umol/L 1.000 0.997–1.003 0.920
Hemoglobin A1c, % 1.177 0.909–1.523 0.216
Brain natriuretic peptide, pg/mL 1.000 1.000–1.000 0.238
Glomerular filtration rate, mL/min 0.993 0.979–1.008 0.362
Lactic dehydrogenase, IU/L* 1.007 1.003–1.011 0.002 1.005 1.001–1.010 0.028
Creatine kinase, IU/L 1.000 0.997–1.003 0.999
Creatine kinase-MB, IU/L 1.014 0.903–1.026 0.315
Heart rate, beat/min 1.006 0.989–1.023 0.472
Left ventricular ejection fraction, % 0.978 0.945–1.012 0.196
Left atrial diameter, mm* 1.121 1.079–1.166 < 0.001 1.109 1.057–1.163 < 0.001
CHA2DS2-VASc score* 1.310 1.082–1.587 0.106
HAS-BLED score 1.403 0.949–2.074 0.289
Antiarrhythmic drugs
 Amiodarone* Reference Reference Reference Reference Reference Reference
 Others antiarrhythmic drugs 1.024 0.682–1.328 0.381 0.833 0.504–1.377 0.477
Ablation protocol
 Circumferential pulmonary vein isolation* Reference Reference Reference Reference Reference Reference
 Circumferential pulmonary vein isolation + Others 1.597 0.886–2.878 0.120 0.680 0.234–1.980 0.479
Electrical cardioversion 1.103 0.648–1.876 0.719
Cumulative triglyceride-glucose index group
 T1* Reference Reference Reference Reference Reference Reference
 T2 5.186 1.501–17.915 0.009 4.949 1.778–13.778 0.002
 T3 18.792 5.855–60.315 < 0.001 8.716 3.371–22.536 < 0.001