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. 2024 Oct 17;22(6):1080–1109. doi: 10.2174/1570159X22666231017141636

Table 5.

Immunization of Tau or antigenic peptides.

Vaccine Target Animal Model Clinical Trial Effect(s) References
AAD vac1 Tau phosphorylation Yes Yes
NCT02031198
NCT02579252
NCT01850238
Lower hippocampal atrophy
(less cognitive decline)
[349-354]
Others Tau phosphorylation/aggregates Yes No Unknown [355]
HHS Vulnerability Disclosure