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The α-synuclein vaccines that have been tested.
| Vaccines | Target | Animal Model | Clinical Trial | Effect(s) | References |
| AFFITOPE®
peptides |
α-syn epitopes | Yes | Yes (subcutaneous) NCT01885494 NCT02267434 |
Cognitive improvement | [367] |
| UB-312 | Oligomeric and fibril protein | Yes | Yes (ongoing) NCT05634876 |
Unknown (still underway) | [368-369] |
| C-type lectin receptor vaccine |
α-syn | Yes | No | Unknown (still underway) | [370] |
| DNA vaccine | α-syn | Yes | No | Not effective | [371, 372] |
| MultiTEP | α-syn | Yes | No | - | [373] |
