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. 2024 Mar 23;7:0333. doi: 10.34133/research.0333

Table 1.

Characteristics of the four main mechanoreceptors in human skin. Reproduced with permission from [21,184]. Copyright, 2018, MDPI.

Meissner corpuscle Pacinian corpuscle Merkel cell Ruffini endings
Category FA-I FA-II SA-I SA-II
Adaptation rate Fast Fast Slow Slow
Location Shallow Deep Shallow Deep
Stimuli frequency (Hz) 10–200 70–100 0.4–100 0.4–100
Density (units/cm2) 140 30 70 10
Spatial resolution (mm) 3–4 >10 0.5 >7
Functional range Object slip, light contact, texture High-frequency, vibrations Static forces with high resolutions Tension deep in the skin and fascia
Receptive field (RF) Small and sharp, 3–5 mm Very large and diffuse, >20 mm Small and sharp, 2–3 mm Large and diffuse, 10–15 mm