Table 5.
Logistic regression predictors clinician and patient-rated cognitive decline after ECT
| MMSE a (n = 352) | EMQ b (n = 205) | |||||
|---|---|---|---|---|---|---|
| Exp. (B) | CI Exp. (B) | p | Exp. (B) | CI Exp. (B) | p | |
| Sex | 0.50 | 0.26–1.00 | 0.049 | 1.12 | 0.55–2.27 | 0.751 |
| Age | 1.02 | 1.00–1.03 | 0.126 | 0.97 | 0.95–0.99 | 0.002 |
| Previously received ECT | 1.18 | 0.56–2.52 | 0.664 | 1.64 | 0.66–4.10 | 0.286 |
| Psychotic features | 1.03 | 0.49–2.14 | 0.939 | 0.35 | 0.14–0.88 | 0.025 |
| Pre-treatment MMSE/EMQ | 1.35 | 1.13–1.63 | 0.001 | 0.97 | 0.96–0.98 | < 0.001 |
Abbreviations: ECT, electroconvulsive therapy; EMQ, Everyday Memory Questionnaire; MMSE, Mini-Mental State Examination.
a
Cognitive decline defined as MMSE reduction ≥2 points pre topost ECT. Model statistically significant, χ 2 (5, n = 352) = 17.96, p = 0.003.
b
Cognitive decline defined as EMQ increase >10% pre to post ECT. Model statistically significant, χ2 (5, n = 205) = 42.95, p < 0.001.