TABLE 2.
emm types/subtypes and the exotoxin gene profiles obtained in invasive and control S. pyogenes isolates
| emm types/subtypes | STs correlation | n cases (%)/n controls (%) | Virulence profiles (n; %) |
|---|---|---|---|
| emm1 | 55 (53.9)/9 (32.1) | ||
| emm1.0 | ST28 (31), ST1357 (1) | 27 (26.5)/5 (17.9) | speA/speG/speJ/smeZ (20/32; 62.5) |
| emm1.3 | ST28 | 27 (26.5)/3 (10.7) | speA/speC/speG/speJ/smeZ (26/30; 86.6) |
| emm1.159 | ST28 | 1 (0.98)/0 | speA/speC/speG/speJ/smeZ (1/1; 100) |
| emm1.40 | ST28 | 0/1 (3.6) | speA/speC/speG/speJ/smeZ/sic (1/1; 100) |
| emm12 | 31 (30.4)/6 (21.4) | ||
| emm12.0 | ST36 (21), ST425 (1) | 18 (17.6)/4 (14.3) | speC/speG/speH/speI/smeZ (15/22; 68.2) |
| emm12.19 | ST36 | 2 (1.9)/0 | speG/speH/speI/smeZ (2/2; 100) |
| emm12.40 | ST36 | 2 (1.9)/0 | speC/speG/speH/speI/smeZ (2/2; 100) |
| emm12.37 | ST242 | 8 (7.8)/2 (7.1) | speC/speG/speH/speI/smeZ (10/10; 100) |
| emm12.128 | ST36 | 1 (0.98)/0 | speG/speH/speI/smeZ (1/1; 100) |
| emm89.0 | ST101 (6), ST1295 (1) | 2 (1.9)/5 (17.8) | speC/speG/ smeZ (6/7; 85.7) |
| emm87.0 | ST62 | 3 (2.9)/1 (3.6) | speC/speG/speJ/ssa/smeZ (3/4; 75) |
| emm4.0 | ST39 | 4 (3.9)/3 (10.7) | speC/ ssa/smeZ (7/7; 100) |
| emm22 | |||
| emm22.0 | ST46 | 0/2 (7.1) | speC/speG/ssa/smeZ (2/2; 100) |
| emm22.24 | ST46 | 1 (0.98)/0 | speA/speG/ssa/smeZ (1/1; 100) |
| emm6.0 | ST382 | 2(1.9)/0 | speC/speG/speH/speI/smeZ (2/2; 100) |
| Others: emm3.93, emm28.0, emm31.12, emm44.0, emm60.11, emm75.0 | ST315, ST458, ST365, ST25, ST53, ST150 | 4 (3.9)/2 (7.1) | Presence of different and varied profiles (see supplementary material) |