Table 3.
Multivariate Cox proportional hazard model of overall survival in all patients. Note:
| Variables | Overall Survival | ||
|---|---|---|---|
| Hazard Ratio (95% Confidence Interval) | P c | ||
| Race | White | Reference | |
| Black | 0.946 (0.781–1.146) | 0.570 | |
| Other a | 0.818 (0.622–1.077) | 0.152 | |
| Marital status | Married | Reference | |
| Not married b | 1.456 (1.291–1.641) | < 0.001 | |
| Missing | 1.015 (0.761–1.354) | 0.921 | |
| Histology | Ductal | Reference | |
| Other d | 0.886 (0.778–1.009) | 0.067 | |
| Grade | Well | Reference | |
| Moderately | 1.194 (0.963–1.479) | 0.106 | |
| Poorly/undifferentiated | 1.427 (1.142–1.783) | 0.002 | |
| Missing | 1.330 (1.046–1.693) | 0.020 | |
| Tumor size | T1 | Reference | |
| T2 | 1.215 (1.057–1.395) | 0.006 | |
| T3/4 | 1.813 (1.448–2.270) | < 0.001 | |
| Missing | 0.608 (0.355–1.041) | 0.070 | |
| Nodal status | N0 | Reference | |
| N1 | 1.197 (1.021–1.403) | 0.027 | |
| N2/3 | 1.612 (1.317–1.973) | < 0.001 | |
| Missing | 2.350 (1.387–3.981) | 0.001 | |
| Estrogen Receptor | Positive | Reference | |
| Negative | 1.403 (0.927–2.123) | 0.110 | |
| Missing | 1.223 (0.714–2.094) | 0.464 | |
| Progesterone Receptor | Positive | Reference | |
| Negative | 1.193 (0.937–1.520) | 0.152 | |
| Missing | 0.855 (0.507–1.441) | 0.557 | |
| Surgery approach | Breast Conserving Surgery | Reference | |
| Mastectomy | 0.755 (0.583–0.979) | 0.034 | |
| Missing | 0.814 (0.618–1.072) | 0.144 | |
| Radiation status | No | Reference | |
| Yes | 0857 (0.736–0.997) | 0.046 | |
| Chemotherapy status | No | Reference | |
| Yes | 0.822 (0.682–0.991) | 0.040 | |
a Other includes American Indian/Alaskan native and Asian/Pacific Islander and Unknown
b Not married includes divorced, separated, single (never married), unmarried or domestic partner, and widowed
cP value was adjusted by a multivariate Cox proportional hazard regression model and bold type indicates significance
d Other represents all pathological types other than invasive ductal breast cancer, including invasive lobular carcinoma, medullary carcinoma, mucinous carcinoma, intraductal papilloma, papillary carcinoma, tubular carcinoma, and so on