Table 2.
NF-1 Associated Comorbidities
| Comorbiditie | Frequency | Percentage |
|---|---|---|
| Cardiovascular abnormalities | 17 | 9.2 |
| Scoliosis | 26 | 14.1 |
| Epilepsy | 21 | 11.4 |
| Tumors | 49 | 26.6 |
| Neurofibrosarcoma | 2 | 1.1 |
| Malignant brain tumor | 21 | 11.4 |
| Glioma | 5 | 2.7 |
| Astrocytoma | 1 | 0.5 |
| Hamartoma | 11 | 6.0 |
| Schwannoma | 2 | 1.1 |
| Other | 2 | 1.1 |
| Extra-neural tumors | 26 | 14.1 |
| Gastrointestinal stromal tumors |
1 | 3.8 |
| Breast cancer | 4 | 15.4 |
| Phaeochromocytoma | 1 | 3.8 |
| Other | 20 | 76.9 |
| Short stature | 17 | 9.2 |
| Macrocephaly/ Hydrocephalus | 26 | 14.1 |
| Leg length discrepancy | 5 | 2.7 |
| Precocious puberty | 4 | 2.2 |
| Headache | 51 | 27.7 |