Table 2. . Allele frequency, genotype frequency and Hardy-Weinberg equilibrium assessment of the candidate genetic variants for diLQTS among self-reported white patients.
| SNPs | Allele frequency in non-Finnish European population in gnomAD | Allele frequency observed in sample | Genotype frequencies, n (%) | HWE (p-value) |
|---|---|---|---|---|
|
SCN5A-G615E rs12720452 |
0.0005178 | 0.000329 | CC: 6079 (99.9) CT: 4 (0.1) TT: 0 (0.00) |
0.980 |
|
KCNE2-I57T rs74315448 |
0.001045 | 0.000986 | TT: 6071 (99.8) TC: 12 (0.2) CC: 0 (0.00) |
0.938 |
|
KCNE1-D85N rs1805128 |
0.01223 | 0.009206 | CC: 5971 (98.1) CT: 112 (1.9) TT: 0 (0.00) |
0.469 |
HWE: Hardy-Weinberg equilibrium.