Table 4. . Comparison of QTc-prolonging drugs prescribed to patients without and with prolonged QTc.

Drug class	Drugs, n (%)	Without prolonged QTc (n = 5,350) (88.0%)	With prolonged QTc (n = 733) (12.0%)	p-value
Antiarrhythmics	Disopyramide	7 (0.1)	0 (0.0)	0.604
	Dofetilide	14 (0.2)	24 (2.6)	<0.001
	Dronedarone	2 (0.0)	3 (0.3)	0.021
	Flecainide	40 (0.7)	10 (1.1)	0.212
	Quinidine	0 (0.0)	1 (0.1)	0.137
	Sotalol	39 (0.7)	21(2.3)	<0.001
	Procainamide	2 (0.0)	1 (0.1)	0.357
Antibiotics	Azithromycin	556 (9.5)	26 (2.8)	<0.001
	Ciprofloxacin	607 (10.4)	54 (5.8)	<0.001
	Clarithromycin	4 (0.1)	1 (0.1)	0.521
	Levofloxacin	290 (5.0)	34 (3.7)	0.102
	Moxifloxacin	11 (0.2)	1 (0.1)	1.000
	Erythromycin	11 (0.2)	3 (0.3)	0.426
Antidepressants	Citalopram	414 (7.1)	43 (4.6)	0.007
	Escitalopram	382 (6.5)	49 (5.3)	0.167
Cholinesterase inhibitor	Donepezil	46 (0.8)	10 (1.1)	0.332
Opioid agonist	Methadone	54 (0.9)	10 (1.1)	0.587
Antipsychotics	Haloperidol	66 (1.1)	12 (1.3)	0.787
	Chlorpromazine	9 (0.2)	2 (0.2)	0.655
Antifungals	Fluconazole	388 (6.7)	58(6.3)	0.712
	Pentamidine	2 (0.0)	2 (0.2)	0.093
Antimalarial	Hydroxychloroquine	173 (3)	33 (3.6)	0.378
Anesthetic	Propofol	2,263 (38.8)	275 (29.7)	<0.001
Antiemetic	Ondansetron	4315 (74.0)	537 (58.0)	<0.001
Oncology	Oxaliplatin	16 (0.3)	2 (0.2)	1.000
Vasodilator	Papaverine	38 (0.7)	21 (2.3)	<0.001
Phosphodiesterase Inhibitor	Cilostazol	32 (0.5)	2 (0.2)	0.312

Bolded p-values indicate p less than 0.05.