Table 3.
Comparison of pulmonary function test, DLCO, and 6MWT results before the treatment, at 1st and 6th months of treatment in patients receiving immunosuppressive therapy.
| Admission | 1st month | 6th month | F | p | difference | |
|---|---|---|---|---|---|---|
| SpO2 % | 90,09±5,22 | 94,1±3,13 | 95,88±2 | 22,285 | <0,001 | Pre<1<6 |
| FVC (L) | 2,43±0,98 | 2,85±1 | 2,75±1,01 | 5,795 | 0,006 | Pre<1,6 |
| FVC % | 68,06±19,09 | 73,95±16,76 | 77,48±18,11 | 12,262 | 0,001 | Pre<1<6 |
| FEV1 (L) | 2,17±0,81 | 2,48±0,88 | 2,36±0,89 | 3,356 | 0,045 | - |
| FEV1 % | 73,81±19,37 | 79,5±20,56 | 81,16±20,62 | 6,024 | 0,005 | Pre<1,6 |
| FEV1/FVC | 91,38±13,05 | 89,23±9,35 | 87,39±11,2 | 0,081 | 0,922 | - |
| DLCO | 8,46±7,17 | 9,23±5,13 | 11,53±6,25 | 1,947 | 0,172 | - |
| DLCO % | 45,1±18,7 | 47,95±16,3 | 54,87±23,46 | 5,123 | 0,011 | Pre<1,6 |
| 6MWT (meter) | 368,11±153,49 | 416,91±160,44 | 435,32±153,22 | 2,964 | 0,086 | - |
| 6MWT Pre SpO2 % | 94,32±2,71 | 94,91±3,07 | 95,41±3,31 | 0,172 | 0,765 | - |
| 6MWT Post SpO2 % | 89,18±7,07 | 89,87±8,38 | 90,67±8,91 | 0,244 | 0,785 | - |
Abbreviations: SpO2: oxygen saturation as measured by pulse oximetry; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; 6MWT: 6-minute walk test. Data are presented as mean±standard deviation unless otherwise stated.