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. 1998 May;72(5):4224–4230. doi: 10.1128/jvi.72.5.4224-4230.1998

TABLE 1.

Overall mutation frequencies

RT No. of plaques screened No. of mutants Mutation frequencya (10−3)
Wild type 13,662 138 8.60
E89G 13,916 108 6.26
M184V 14,804 104 5.53
E89G/M184V 7,173 99 12.30
a

Corrected for background by subtracting the spontaneous background frequency of 1.50 × 10−3 from the frequency observed for a given RT. Spontaneous background was measured by using uncopied gapped M13mp2 DNA.