Table 2.
Combinations of mRNA species detected in M1 slices obtained from Drd1a-tdTomato and Drd2Cre::Ai14 mice
| mRNA Combinationa | Drd1a-tdTomato | Drd2Cre::Ai14 | ||
|---|---|---|---|---|
| Layer II-III [Mean ± SEM (%)] | Layers V-VI [Mean ± SEM (%)] | Layer II-III [Mean ± SEM (%)] | Layers V-VI [Mean ± SEM (%)] | |
| All vGlut1 | 62 ± 10 (100) | 52 ± 5 (100) | 67 ± 6 (100) | 48 ± 4 (100) |
| vGlut1 only | 53 ± 9 (85) | 12 ± 2 (23) | 42 ± 5 (63) | 44 ± 3 (92) |
| vGlut1/tdTomatob | 9 ± 5 (15) | 40 ± 6 (77) | 25 ± 3 (37) | 4 ± 1 (8) |
| All vGAT1 | 10 ± 1 (100) | 8 ± 2 (100) | 12 ± 2 (100) | 9 ± 1 (100) |
| vGAT1 only | 3 ± 1 (30) | 2 ± 1 (25) | 8 ± 2 (67) | 5 ± 1 (56) |
| vGAT1/tdTomatob | 7 ± 1 (70) | 6 ± 1 (75) | 4 ± 1 (33) | 4 ± 1 (44) |
| All vGlut1/vGAT1 | 1 ± 1 (100) | 0 (0) | 2 ± 1 (100) | 1 ± 0.3 (100) |
| vGlut1/vGAT1 only | 0 (0) | 0 (0) | 1 ± 0.3 (50) | 1 ± 0.2 (100) |
| vGlut1/vGAT1/tdTomatob | 1 ± 1 (100) | 0 (0) | 1 ± 1 (50) | 0 (0) |
| All tdTomatob | 18 ± 5 (100) | 46 ± 5 (100) | 30 ± 2 (100) | 9 ± 1 (100) |
| tdTomato onlyb | 15 ± 5 (83) | 44 ± 5 (95) | 29 ± 3 (96) | 3 ± 1 (39) |
| tdTomato/D2b,c | 3 ± 1 (17) | 2 ± 1 (5) | – | – |
| tdTomato/D1b,c | – | – | 1 ± 1 (4) | 6 ± 1 (61) |
The data presented in the table correspond to the Euler diagrams shown in Fig. 2A.
tdTomato signifies D1+ neurons in Drd1a-tdTomato mice or D2+ neurons in Drd2Cre::Ai14 mice.
Counting of Drd1a expressing cells in Drd1a-tdTomato mice and Drd2 expressing in Dr2Cre::Ai14 mice was not performed due to the confounding effects of partial receptor sequences included in the transgenes.