Table 3.
Colocalization analysis showing the immune cell-related traits and pre-eclampsia/eclampsia GWAS associations shared a causal SNP in the given region.
| Outcome | Exposures | PPH0 | PPH1 | PPH2 | PPH3 | PPH4 |
|---|---|---|---|---|---|---|
| Pre-eclampsia/eclampsia | Lymphocyte absolute count | 5.26E-04 | 4.71E-02 | 1.06E-05 | 0 | 9.52E-01 |
| T cell absolute count | 9.21E-06 | 4.71E-02 | 1.86E-07 | 0 | 9.53E-01 | |
| CD28- CD25++ CD8+ T cell absolute count | 3.88E-06 | 5.35E-04 | 7.24E-06 | 0 | 9.99E-01 |
PPH: posterior probability of hypothesis; PPH4 > 95% indicates that the immune cell-related traits and pre-eclampsia/eclampsia share a single causal SNP.