TABLE 3.
Coreceptor use of env clones pseudotyped with luciferase-expressing virus
| Virus (clone) | Relative light units/10 sa
|
|||
|---|---|---|---|---|
| No coreceptor | CCR3 | CCR5 | CXCR4 | |
| DS (12b) | 215 | 249 | 2,333 | 565 |
| DS (C13) | 503 | 530 | 7,507 | 898 |
| DS (C17) | 401 | 1,706 | 45,524 | 1,186 |
| RC (7) | 282 | 377 | 12,336 | 510 |
| RC (48) | 251 | 424 | 4,469 | 610 |
| RC (52) | 222 | 157 | 765 | 124 |
| RC (56) | 138 | 312 | 18,353 | 117 |
| RC (59) | 149 | 240 | 1,370 | 178 |
| KJ (A1) | 124 | 564 | 2,164 | 2,270 |
| KJ (A7) | 135 | 215 | 3,065 | 146 |
| BORI (11A) | 320 | 2,235 | 14,473 | 590 |
| BORI-15 (4C) | 340 | 1,989 | 59,399 | 603 |
| BORI-15 (5C) | 259 | 269 | 2,663 | 399 |
| BORI-15 (7A) | 779 | 478 | 9,820 | 1,166 |
| BaL | 543 | 99,308 | 453,053 | 269 |
| JRFL | 378 | 2,328 | 50,838 | 424 |
| YU-2 | 205 | 483 | 9,072 | 189 |
a
Geometric mean of multiple experiments (3 to 15) except for clones KJ (A1) and KJ (A7), which were assayed twice. Values in boldface were significant (0.0007 ≤ P ≤0.068); values underlined represent reproducible use of a coreceptor that did not reach significance, using Wilcoxon’s signed ranks test.