Table 1.

Combined effects of simvastatin and amfenac on IL-1α (10 pg/ml) or IL-1β (5 pg/ml)-induced inflammatory responses in human ARPE-19 cell cultures

Exposure	IL-1α	IL-1α	IL-1α			IL-1β
Measurement	NF-κB	PGE2	IL-6	IL-8	MCP-1	IL-6	IL-8	MCP-1
Simvastatin	↓	↓	–	↓	↓	↓	↓	↓
Amfenac	–	–	–	↓	–	–	–	↓
Amfenac + simvastatin	↓	–	–	↓	–	↓	↓	↓