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. 2023 Sep 30;47(4):895–902. doi: 10.1007/s40618-023-02205-1

Table 3.

Subgroup analysis examining differential effects of P2Y12 inhibitors on the risk of major osteoporotic fractures

Subgroup Hazard ratio 95% Confidence interval P value for interaction
Age group 0.80
 ≤ 65 years 0.66 0.38 1.13
 > 65 years 0.61 0.41 0.91
Sex 0.34
 Male 0.53 0.34 0.82
 Female 0.71 0.45 1.13
Diabetes 0.18
 No 0.51 0.33 0.76
 Yes 0.81 0.49 1.35
Baseline eGFR 0.47
 ≥ 60 mL/min 0.67 0.45 0.99
 < 60 mL/min 0.50 0.29 0.88
Previous fracture 0.14
 No 0.56 0.39 0.80
 Yes 0.93 0.45 1.90