TABLE 5.

Least-squared mean tests of significance (including the standard error of the mean, SEM) between homozygous-edited (CD163 ^ΔE7/ΔE7) and homozygous-unedited (null, CD163 ^+/+) pigs for phenotypic characteristics across the lifecycle of the pigs. Descriptive statistics from non-edited animals of the same breeding line from two of genus PIC’s nucleus farms in 2021 are also included for comparison (the “reference population”).

	Pigs in observational studies				Reference population a
	CD163 ΔE7/ΔE7		CD163 +/+		—
Trait b	N	LS mean (SEM)	N	LS mean (SEM)	N	Mean	SD	Min	Max
Early life traits
BWT	121	1.30 (0.03)	138	1.26 (0.03)	30,464	1.39	0.34	0.20	2.70
TEAT	121	15.91 (0.12)	138	15.97 (0.12)	12,062	15.69	1.25	6	20
Finishing traits
WT140	55	93.17 (1.30)	55	88.77 (1.30)	12,064	97.07	9.74	56.00	136.50
LDG	55	636.96 (8.29)	55	611.83 (8.29)	12,064	685.65	68.28	397.00	942
BF	55	8.98 (0.23) c	55	9.99 (0.23) c	12,066	8.48	2.23	3.3	22.7
LD	55	63.54 (0.65)	55	65.09 (0.64)	12,064	59.66	5.93	34.4	93.4
Female reproductive traits
GL	6	116.2 (0.4)	6	116.8 (0.4)	992	116.6	1.5	112		123
TNB	6	12.7 (1.1)	6	13.3 (1.1)	992	15.6	3.4	1		25
NBA	6	11.8 (1.1)	6	13.0 (1.1)	992	14.2	3.2	0		23
NBD	6	0.8 (0.4)	6	0.3 (0.4)	992	1.4	1.6	0		11
MUM	6	0.2 (0.1)	6	0.0 (0.1)	992	0.5	0.9	0		8

^a The “reference population” includes all historical data collected from data from the non-edited animals of the same breeding line at two of the Genus PIC’s nucleus farms in calendar year 2021.

^b BWT, individual piglet birth weight, kg; TEAT, total teat count; WT140, individual weight of pig at 140 days of age, kg; LDG, lifetime daily gain, g per day; BF, ultrasound predicted 10th rib backfat depth, mm; LD, ultrasound predicted 10th rib loin depth, mm; GL, gestation length, days; TNB, total number of piglets born; NBA, number of piglets born alive; NBD, number of piglets born dead ; MUM, number of mummified piglets.

^c p < 0.05. Not significant after Bonferroni multiple-test correction.