Table 2.
Infectious consequences in patients with ALD cirrhosis (abstinent and drinkers) and AH.
| Parameter | ARLD-A (n=39) |
ARLD-D (n=11) |
AH (n=37) |
|---|---|---|---|
| Positive blood culture | 0/39 | 0/11 | 1/36 (3) [1 patient excluded as data not known] |
| Microbial growth in urine (%) | 0/39 | 0/11 | 1/37 [enterococcus faecalis] |
| Presence of CXR changes to support a diagnosis of pneumonia | 0/39 | 0/11 | 12/37 [n=7 consolidation, n=5 atelectasis +/- pleural effusion |
| Bacterial peritonitis on ascitic tap | 0/39 | 0/11 | 4/37 [n=1 had growth of Clostridium Tertium, n=1 had growth of Enterococcus Cloacae, n=2 had a polymorph count >250 but no bacterial growth] |
| Infection on skin swabs | 0/39 | 0/11 | 2/37 [n=1 patient had fournier’s gangrene, with multiple organisms on swab, one patient had growth of Staph Aureus] |
| Infection on nasal/throat swabs | 0/39 | 0/11 | 2/37 [n=2 tested positive for COVID19] |
| Infection on stool culture | 0/39 | 0/11 | 1/37 [n=1 patient had C diff+ve stools] |
| Antibiotics (during hospital admission) | 0/39 | 0/11 | 26/37 [16/26 were on antibiotics at the time of blood sampling] |
Electronic patient records at University Hospitals Birmingham were reviewed to obtain data on the presence of infections (up to 6 months after initial blood sampling). Electronic drug charts were reviewed for evidence of antibiotic use. CXR, chest X-ray.