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. 2024 Mar 13;98(5):1241–1252. doi: 10.1007/s00204-024-03685-7

Table 2.

Some common PFAS substances and the estimated serum half-lives in three species (Olsen et al. 2007; Fenton et al. 2021)

Chemical name Abbreviation Formula Human Monkey Rat
Perflurobutanoic acid PFBA C4HF7O2 3 d 1.7 d 1–9 h
Perfluorohexanoic acid PFHxA C6HF11O2 32 d 2.4–5.3 h 0.4–0.6 h
Ammonium salt of hexafluoropylene oxide dimer acid

GenX

HFPO DA

C6HF11O3 4–6 d NA 3–8 h
Perfluoroheptanoic acid PFHpA C7HF13O2 1.2–2.5 NA 1.2 -2.4 h
Perfluorooctanoic acid PFOA C8HF15O2 2.1–3.8 y 21–30 d 2–6 d
Perfluorononanoic acid PFNA C9HF17O2 2.5–4.3 y NA 1.4–55 d
Perfluorodecanoic acid PFDA C10HF19O2 3.1–4.4 y NA NA
Perfluorobutane sulfonic acid PFBS C4HF9O3S 28 d 3.5–4.0 d 2.1–4.5 h
Perfluorohexane sulfonic acid PFHxS C6HF13O3S 5.3–8.5 y 87–141 d 1.8–6.8 d
Perfluorooctane sulfonic acid PFOS C8H2F17NO2H 3.4–5.0 y 110–132 d 62–41 d

d days, h hour, y year, NA not available