Table 4.
Univariate analyses results of the relationship between quartiles of plasma n-3 and n-6 polyunsaturated fatty acids and depression in American adults: NHANES, 2011–2012.
| PUFA, μmol/L, N (%) | Total | Without depression | Depression | χ2 | p value |
|---|---|---|---|---|---|
| LA(18:2n-6) | 1,593(100) | 1,467(92.52) | 126(7.48) | ||
| [1430.00, 2989.84] | 373(24.61) | 341(24.57) | 32(25.06) | 0.23 | 0.88 |
| [2989.84, 3451.86] | 391(25.28) | 365(25.51) | 26(22.52) | ||
| [3451.86, 4026.28] | 413(25.00) | 383(25.10) | 30(23.72) | ||
| [4026.28, 15900.00] | 416(25.11) | 378(24.82) | 38(28.70) | ||
| GLA(18:3n-6) | 1,549(100) | 1,428(92.80) | 121(7.20) | ||
| [6.61, 30.22] | 371(24.99) | 341(25.22) | 30(21.93) | 0.37 | 0.77 |
| [30.22, 42.89] | 368(24.72) | 343(24.73) | 25(24.55) | ||
| [42.89, 64.91] | 411(25.29) | 381(25.41) | 30(23.70) | ||
| [64.91, 391.00] | 399(25.01) | 363(24.63) | 36(29.82) | ||
| ALA(18:3n-3) | 1,592(100) | 1,466(92.52) | 126(7.48) | ||
| [16.80, 50.91] | 379(24.98) | 346(24.84) | 33(26.69) | 0.36 | 079 |
| [50.91, 68.27] | 384(24.89) | 359(25.22) | 25(20.89) | ||
| [68.27, 96.45] | 414(25.08) | 384(25.19) | 30(23.72) | ||
| [96.45, 803.00] | 415(25.05) | 377(24.75) | 38(28.70) | ||
| SDA(C18:4n-3) | 1798(100) | 1,648(92.48) | 150(7.52) | ||
| [0.17, 2.05] | 500(24.74) | 463(25.11) | 37(20.28) | 1.98 | 0.11 |
| [2.05, 3.18] | 475(25.22) | 438(25.53) | 37(21.48) | ||
| [3.18, 5.13] | 408(24.89) | 376(25.06) | 32(22.89) | ||
| [5.13, 104.00] | 415(25.13) | 371(24.30) | 44(35.35) | ||
| DGLA(20:3n-6) | 1934(100) | 1787(93.16) | 147(6.84) | ||
| [29.00, 122.75] | 560(24.02) | 529(24.33) | 31(19.83) | 2.20 | 0.09 |
| [122.75, 161.13] | 527(25.91) | 492(26.49) | 35(18.02) | ||
| [161.13, 197.92] | 393(24.29) | 358(24.08) | 35(27.22) | ||
| [197.92, 465.00] | 454(25.77) | 408(25.10) | 46(34.92) | ||
| EDA(20:2n-6) | 1826(100) | 1,679(92.70) | 147(7.30) | ||
| [8.75, 18.09] | 439(24.32) | 410(22.58) | 29(23.86) | 0.76 | 0.52 |
| [18.09, 22.18] | 444(24.74) | 411(23.35) | 33(19.05) | ||
| [22.18, 27.71] | 468(25.86) | 432(24.11) | 36(23.99) | ||
| [27.71, 134.00] | 475(25.07) | 426(22.66) | 49(33.09) | ||
| AA(20:4n-6) | 2041(100) | 1878(92.66) | 163(7.34) | ||
| [187.00, 713.84] | 533(24.96) | 500(25.51) | 33(18.09) | 1.81 | 0.14 |
| [713.84, 868.54] | 515(24.97) | 476(24.83) | 39(26.75) | ||
| [868.54, 1040.25] | 492(25.05) | 450(24.60) | 42(30.71) | ||
| [1040.25, 2570.00] | 501(25.02) | 452(25.07) | 49(24.44) | ||
| EPA(20:5n-3) | 2041(100) | 1878(92.66) | 163(7.34) | ||
| [8.76, 35.96] | 551(24.89) | 508(24.84) | 43(25.55) | 1.24 | 0.29 |
| [35.96, 53.19] | 492(24.87) | 450(24.72) | 42(26.76) | ||
| [53.19, 82.38] | 512(25.14) | 465(24.64) | 47(31.44) | ||
| [82.38, 1090.00] | 486(25.10) | 455(25.80) | 31(16.25) | ||
| DTA(22:4n-6) | 1975(100) | 1822(92.96) | 153(7.26) | ||
| [1.71, 20.23] | 543(24.87) | 522(25.82) | 21(12.76) | 4.32 | 0.005* |
| [20.23, 25.63] | 489(24.97) | 485(25.49) | 31(18.42) | ||
| [25.63, 32.48] | 461(24.71) | 412(23.94) | 49(34.66) | ||
| [32.48, 204.00] | 482(25.44) | 430(24.76) | 52(34.16) | ||
| DHA(22:6n-3) | 2032(100) | 1870(92.68) | 162(7.32) | ||
| [25.70, 107.61] | 449(24.80) | 245(25.10) | 32(23.58) | 3.76 | 0.01* |
| [107.61, 144.05] | 480(25.17) | 247(23.14) | 55(44.07) | ||
| [144.05, 195.42] | 519(24.82) | 289(25.38) | 32(14.75) | ||
| [195.42, 918.00] | 584(25.22) | 326(26.38) | 43(17.61) | ||
| DPA6(22:5n-6) | 1982(100) | 1828(92.72) | 154(7.28) | ||
| [2.18, 14.56] | 485(24.89) | 466(25.78) | 19(13.51) | 9.34 | < 0.001* |
| [14.56, 19.22] | 489(24.94) | 461(25.85) | 28(13.33) | ||
| [19.22, 25.15] | 492(24.91) | 444(23.87) | 48(38.03) | ||
| [25.15, 126.00] | 516(25.27) | 457(24.49) | 59(35.12) | ||
| DPA3 (22:5n-3) | 1998(100) | 1844(92.82) | 154(7.18) | ||
| [12.60, 40.17] | 562(24.77) | 534(25.55) | 28(14.67) | 2.11 | 0.10 |
| [40.17, 49.70] | 497(25.21) | 460(25.22) | 37(25.10) | ||
| [49.70, 62.06] | 451(24.85) | 412(24.63) | 39(27.80) | ||
| [62.06, 229.00] | 488(25.16) | 438(24.60) | 50(32.43) | ||
| Total n-3 | 1,369(100) | 1,260(92.56) | 368(25.03) | ||
| [91.58, 268.26] | 310(24.82) | 284(25.26) | 26(19.34) | 1.35 | 0.26 |
| [268.26, 344.47] | 355(25.08) | 330(24.49) | 25(32.39) | ||
| [344.47, 441.24] | 336(25.07) | 303(24.49) | 33(32.35) | ||
| [441.24, 1917.50] | 368(25.03) | 343(25.76) | 25(15.93) | ||
| Total n-6 | 1,323(100) | 1,226(93.55) | 97(6.45) | ||
| [2913.92, 4193.90] | 321(24.89) | 300(25.47) | 21(16,54) | 0.84 | 0.47 |
| [4193.90, 4662.68] | 328(25.09) | 307(25.22) | 21(23.24) | ||
| [4662.68, 5296.08] | 332(25.00) | 308(24.59) | 24(30.94) | ||
| [5296.08, 17189.00] | 342(25.01) | 311(24.72) | 31(29.28) | ||
| n-6/n-3 ratio | 1,198(100) | 1,107(93.52) | 91(6.48) | ||
| [2.25, 11.38] | 311(24.88) | 290(25.05) | 21(22.30) | 2.85 | 0.04* |
| [11.38, 14.17] | 312(25.10) | 287(25.12) | 25(24.84) | ||
| [14.17, 16.75] | 296(25.02) | 269(24.12) | 27(37.95) | ||
| [16.75, 28.60] | 279(25.01) | 261(25.71) | 18(14.91) | ||
| AA/EPA | 2040(100) | 1877(92.65) | 163(7.35) | ||
| [0.36, 11.19] | 494(24.79) | 468(25.62) | 26(14.30) | 2.35 | 0.07 |
| [11.19, 16.85] | 500(25.14) | 450(24.45) | 50(33.87) | ||
| [16.85, 23.24] | 468(25.04) | 435(25.22) | 33(22.71) | ||
| [23.24, 73.13] | 578(25.03) | 524(24.71) | 54(29.12) | ||
| AA/DHA | 2032(100) | 1870(92.68) | 162(7.32) | ||
| [0.77, 4.47] | 575(25.00) | 545(26.11) | 30(10.88) | 7.44 | < 0.001* |
| [4.47, 6.15] | 532(24.96) | 489(24.88) | 43(26.08) | ||
| [6.15, 7.73] | 487(24.88) | 437(24.31) | 50(32.16) | ||
| [7.73, 18.91] | 438(25.16) | 399(24.71) | 39(30.88) |
*p < 0.05.