Table 6.

Stratified analyses of the association of plasma n-3 and n-6 polyunsaturated fatty acids levels with depression in American adults: NHANES, 2011–2012.^a

PUFA, μmol/L, N	Male	OR (95% CI)	p trendb	Female	OR (95% CI)	p trendb
AA(20:4n-6)	n = 1,039			n = 1,002
	[187.00, 711.80](n = 290)	Ref	0.68	[295.00, 718.63](n = 243)	Ref	0.99
	[711.80, 856.29](n = 273)	0.92(0.37, 2.29)		[718.63, 878.13](n = 242)	1.99(1.00, 3.93)
	[856.29, 1033.88](n = 242)	1.26(0.48, 3.26)		[878.13, 1053.00](n = 250)	2.44(1.36, 4.39)
	[1033.88, 2570.00](n = 234)	0.84(0.34, 2.09)		[1053.00, 2560.00](n = 267)	1.41(0.65, 3.05)
DHA(22:6n-3)	n = 1,033			n = 999
	[34.30, 99.89](n = 273)	Ref	0.30	[25.70, 116.76](n = 176)	Ref	0.005*
	[99.89, 136.00](n = 253)	2.06(0.53, 8.08)		[116.76, 152.40](n = 227)	2.24(0.86, 5.88)
	[136.00, 187.07](n = 258)	1.11(0.25, 4.90)		[152.40, 205.87](n = 261)	0.50(0.28, 0.87)
	[187.07, 918.00](n = 249)	1.96(0.91, 4.22)		[205.87, 799.00](n = 335)	0.49(0.25, 0.96)
DPA3 (22:5n-3)	n = 1,014			n = 984
	[12.6 40.79](n = 271)	Ref	0.15	[15.10, 39.97](n = 291)	Ref	0.13
	[40.79, 49.90](n = 259)	1.66(0.49, 5.62)		[39.97, 49.39](n = 238)	2.06(1.00, 4.25)
	[49.90, 61.18](n = 240)	2.32(0.78, 6.86)		[49.39, 62.65](n = 211)	2.08(0.96, 4.51)
	[61.18, 229.00](n = 244)	2.40(0.78, 7.42)		[62.65, 198.00](n = 244)	2.39(1.28, 4.47)
AA/DHA	n = 1,033			n = 999
	[0.92, 4.82](n = 266)	Ref	0.17	[0.77, 4.36](n = 309)	Ref	0.004*
	[4.82, 6.52](n = 254)	2.38(0.81, 7.00)		[4.36, 5.98](n = 278)	1.94(0.77, 4.88)
	[6.52, 8.12](n = 244)	2.07(0.73, 5.84)		[5.98, 7.28](n = 243)	2.32(1.12, 4.81)
	[8.12, 18.91](n = 269)	0.89(0.19, 4.19)		[7.28, 17.40](n = 169)	4.09(2.14, 7.84)

*p < 0.05.

^aAnalyses were adjusted for age, sex, education, race/ethnicity, ratio of family income to poverty and CVH except the stratification variable, and only the statistically significant results were shown after controlling all potential confounders.

^bTest for trend based on the variable containing a median value for each quartile.