| Our analysis of reported real-world cases underscores the detrimental impact of drug–drug interactions (DDIs) between antiretrovirals (ARVs) and over-the-counter medications. | |
| It emphasizes the critical necessity for comprehensive medication reconciliation, including non-prescription drugs. | |
| It highlights the continued clinical significance of relevant DDIs associated with boosted ARV. | |
| It highlights the importance of reporting real-world cases of DDIs. |
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