Table 2.
Clinical characteristics and echocardiographic findings at the time the patient met the EOLIA criteria or of the worst PaO2/FiO2 within the first 7 days after tracheal intubation
| Variable | n (available/total) | All patients n = 283 |
|---|---|---|
| Clinical characteristics | ||
| Time from intubation to worst PaO2/FiO2 (days) | 283/283 (100) | 2 [0;4] |
| Vasopressor support, n (%) | 283/283 (100) | 95 (34) |
| Inotropic support, n (%) | 283/283 (100) | 4 (1) |
| PaO2/FiO2 (mmHg) | 283/283 (100) | 78 [56;94] |
| PaCO2 (mmHg) | 283/283 (100) | 52 [45;62] |
| pH | 283/283 (100) | 7.33 [7.32;7.38] |
| Plateau pressure (cmH2O) | 263/283 (93) | 27 [24;30] |
| PEEP (cmH2O) | 283/283 (100) | 10 [8;13] |
| Driving pressure (cmH2O) | 263/283 (93) | 16 [13;19] |
| Respiratory rate (cycle/min) | 283/283 (100) | 28 [24;32] |
| Tidal volume (mL/kg PBW) | 283/283 (100) | 6.3 [5.9;7] |
| Central venous pressure (mmHg) | 108/283 (38) | 10 [8;12] |
| Echocardiographic findings | ||
| LVEF (%) | 231/283 (82) | 59 [52;66] |
| LVOT VTI (cm) | 230/283 (81) | 20.8 [17;24.2] |
| E/A ratio | 214/283 (76) | 0.95 [0.77;1.17] |
| RVEDA/LVEDA | 232/283 (82) | 0.74 [0.59;0.88] |
| Paradoxical septal motion, n (%) | 236/283 (83) | 93 (39) |
| RV fractional area change (%) | 222/283 (78) | 42 [33;48] |
| Pulmonary acceleration time (ms) | 181/283 (64) | 83 [66;100] |
Categorical variables are expressed as number (%) and continuous variables as median [interquartile ranges]. PEEP Positive End-Expiratory Pressure, PBW Predicted Body Weight, LVEF Left Ventricular Ejection Fraction, LVOT VTI Left Ventricular Outflow Tract Velocity–Time Integral, RV Right Ventricular