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. 1998 May;72(5):4288–4296. doi: 10.1128/jvi.72.5.4288-4296.1998

FIG. 3.

FIG. 3

Assessment of pretreatment HVR1 quasispecies heterogeneity by clonal frequency analysis (left) and analysis of the temporal changes in HVR1 quasispecies by HTA (right) in responder-relapse patients 6 (A) and 8 (B). For clonal frequency analysis, representative pretreatment HVR1 clones were hybridized to a patient-specific, radiolabeled HVR1 probe and subjected to heteroduplex analysis. For HTA, heterogeneous HVR1 PCR products from the indicated time points were subjected to heteroduplex analysis.