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. 2024 Mar 26;14:7129. doi: 10.1038/s41598-024-57383-6

Table 2.

Group differences in brain volumes compared with retired athletes with rmTBI and HC in Reader 1.

Volume, cm3, mean ± SD Regional volume/TBV ratio, × 10−3 mean ± SD
Retied athletes with rmTBI HC p value Retied athletes with rm TBI HC p value
n = 27 n = 23 n = 27 n = 23
TBV 1.12 ± 0.13 × 103 1.17 ± 0.12 × 103 ns
MB 0.14 ± 0.05 0.22 ± 0.03  < 0.001** 0.13 ± 0.05 0.19 ± 0.03  < 0.001**
Put 11.0 ± 1.55 11.2 ± 1.24 ns 9.85 ± 1.11 9.61 ± 0.86 ns
GP 3.18 ± 0.43 3.14 ± 0.48 ns 2.87 ± 0.44 2.70 ± 0.44 ns
CN 8.65 ± 1.37 9.30 ± 1.14 ns 7.74 ± 0.79 7.94 ± 0.73 ns
Thal 13.6 ± 2.08 14.9 ± 2.01 0.04* 12.2 ± 1.22 12.7 ± 1.25 ns
Hipp 7.41 ± 1.05 7.73 ± 1.10 ns 6.65 ± 0.68 6.61 ± 0.77 ns
Amy 3.89 ± 0.66 4.01 ± 0.55 ns 3.48 ± 0.45 3.44 ± 0.46 ns
CC 13.9 ± 1.77 15.9 ± 2.32  < 0.001** 12.5 ± 1.63 13.6 ± 1.81 0.03*

rmTBI repetitive mild traumatic brain injury, HC healthy control, SD standard deviation, TBV, total brain volume, ns, not significant, MB mammillary bodies, Put putamina, GP globus pallida, CN caudate nuclei, Thal thalami, Hipp hippocampi, Amy amygdalae, CC corpus callosum **p < 0.006, *p < 0.05.