Table 2.
Cost-effectiveness of prophylactic LPI versus that of observation (base-case and scenarios with different ages at entry and exit from the cohort).
| Observation period | Strategy | Cost (JPY) | Incremental cost (JPY) | QALY | Incremental QALY | ICER (JPY/QALY) |
|---|---|---|---|---|---|---|
| 40–59 years of age (20-year horizon, base-case) | LPI | 449,050 | 55,572 | 16.67 | 0.02 | 2,287,662 |
| Observation | 393,478 | 16.65 | ||||
| 40–54 years of age (15-year horizon) | LPI | 368,602 | 60,784 | 13.10 | 0.02 | 3,958,450 |
| Observation | 307,818 | 13.09 | ||||
| 40–49 years of age (10-year horizon) | LPI | 280,195 | 66,526 | 9.16 | 0.01 | 7,610,359 |
| Observation | 213,669 | 9.15 | ||||
| 50–69 years of age (20-year horizon) | LPI | 449,037 | 55,615 | 16.67 | 0.02 | 2,294,626 |
| Observation | 393,421 | 16.65 | ||||
| 50–64 years of age (15-year horizon) | LPI | 368,596 | 60,803 | 13.10 | 0.02 | 3,966,008 |
| Observation | 307,794 | 13.09 | ||||
| 50–59 years of age (10-year horizon) | LPI | 280,194 | 66,531 | 9.16 | 0.01 | 7,617,443 |
| Observation | 213,663 | 9.15 | ||||
| 40–99 years of age | LPI | 880,510 | 23,196 | 35.40 | 0.19 | 124,675 |
| (60-year horizon) | Observation | 857,314 | 35.21 |
LPI laser peripheral iridotomy, JPY Japanese Yen, QALY quality-adjusted life-year, ICER incremental cost-effectiveness ratio.