TABLE 2.
Comparison of the divergence between PTLV strainsa
| Strain | Gene | % nt difference from corresponding gene of:
|
|||||
|---|---|---|---|---|---|---|---|
| HTLV-2b NRA | HTLV-2c KAY1 | HTLV-2d Efe2 | STLV-2 PP1664 | HTLV-1a ATK1 | STLV-L PH969 | ||
| HTLV-2a Mo | LTR | 7.4 | 5.0 | 10.7 | 31.6 | 42.1 | 44.6 |
| gag | 4.1 | 6.6 | 23.3 | 30.6 | 31.9 | ||
| pol | 4.9 | 6.7 | 23.3 | 34.5 | 34.8 | ||
| env | 4.4 | 1.0 | 6.5 | 23.8 | 34.6 | 32.0 | |
| tax/rex | 2.2 | 0.4 | 3.3 | 10.7 | 21.4 | 22.6 | |
| HTLV-2b NRA | LTR | 6.0 | 7.2 | 29.8 | 42.6 | 44.2 | |
| gag | 6.7 | 23.1 | 30.0 | 31.5 | |||
| pol | 6.5 | 22.6 | 35.0 | 34.6 | |||
| env | 3.9 | 6.9 | 23.6 | 34.3 | 32.4 | ||
| tax/rex | 2.2 | 2.4 | 10.4 | 22.0 | 22.3 | ||
| HTLV-2c KAY1 | LTR | 10.0 | 32.0 | 42.0 | 44.0 | ||
| gag | |||||||
| pol | |||||||
| env | 5.7 | 20.0 | 32.8 | 28.1 | |||
| tax/rex | 3.3 | 12.3 | 21.4 | 22.1 | |||
| HTLV-2d Efe2 | LTR | 29.2 | 43.1 | 43.4 | |||
| gag | 22.8 | 30.2 | 40.0 | ||||
| pol | 22.4 | 34.6 | 34.7 | ||||
| env | 22.9 | 33.5 | 31.8 | ||||
| tax/rex | 11.5 | 22.5 | 22.4 | ||||
| STLV-2 PP1664 | LTR | 43.3 | 44.5 | ||||
| gag | 30.6 | 30.2 | |||||
| pol | 35.5 | 34.5 | |||||
| env | 36.1 | 33.1 | |||||
| tax/rex | 21.9 | 22.9 | |||||
| HTLV-Ia ATK1 | LTR | 42.3 | |||||
| gag | 30.7 | ||||||
| pol | 36.6 | ||||||
| env | 34.7 | ||||||
| tax/rex | 21.1 | ||||||
Transitions and transversions are scored equally. For details of the strains, see Materials and Methods. LTR, entire LTR (except for HTLV-2c, for which only 479 nt is available); gag, entire gag ORF; pol, entire pol ORF without protease, starting from the protease cleavage site at the C terminus from the protease; env, entire env ORF (except for HTLV-c, for which only 610 nt, including the entire gp21-coding sequence, is available); tax/rex, entire second ORF of rex, overlapping with part of the tax ORF (the ATK1 and PH969 rex second ORFs are 60 and 36 nt longer, respectively; this extension compared with HTLV-2 was excluded from the comparison). The distances between HTLV-2d genes and those of the other PTLV types and HTLV-2 subtypes are in boldface.