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. Author manuscript; available in PMC: 2025 Feb 1.
Published in final edited form as: Magn Reson Med. 2023 Oct 17;91(2):681–686. doi: 10.1002/mrm.29888

Figure 2.

Figure 2.

Mean (± SEM) substrate, and downstream HOD and metabolite concentration time courses, following sc administration of, from left to right, Glc (n = 7), Act (n = 6), and βHB (n = 6) as 1-M substrate solutions (in saline) at a dose of 25μL/g-body-weight. As per Methods, using the known natural-abundance HOD concentration, substrate and metabolite T1 and T2 relaxation time constants, and labeling stoichiometry, 2H resonance amplitudes were converted to aqueous molar concentrations. Bottom panels: substrate and downstream metabolite time courses. Top panels: downstream HOD time courses.