Table 1.

Multi-target stool DNA demonstrates higher specificity in younger patients with normal colonoscopy

Patient Population	Specificity
Imperiale et al [39]
No CRC or advanced adenoma*, all ages	86.6%
Negative colonoscopy, all ages	90%
No CRC or advanced adenoma*, age 50-64	91.5%
Negative colonoscopy, age 50-64	94%
Redwood et al [40]
No CRC or advanced adenoma*, all ages	91%
Negative colonoscopy, all ages	93%

^*Patients with non-advanced lesions, hyperplastic polyps and other findings (e.g. diverticulitis) included in specificity calculation