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CBDQ forms adducts with cysteine residues. (A) Scheme showing oxidation of CBD and formation of CBDQ-cystine adduct. Spectra of (B) synthetic CBDQ and (C) vaped commercial CBD oil (Liberty, Gorilla Glue, 750 mg/mL) reacted with the cysteine-containing model peptide TpepKC (AcAVAGKCAGAR). For both, adducts formed between CBDQ and the Cys residue exclusively based on b and y ion assignment (Figure S5).
